Navigation

Search This Site

Seed Funding

seed funding review

The UVA Brain Institute offers a seed funding program for cross-grounds collaborative research projects. The purpose of this program is to bring neuroscience investigators together to tackle important questions and perform transformative work that will differentiate our research enterprise. It is anticipated that these initiatives require diverse expertise, and involve investigative teams from a variety of disciplines and/or Schools across grounds. Proposed projects may be on any subject related to neuroscience. Evidence of prior collaboration is not required, and the creation of new partnerships is encouraged. Submitted proposals should provide evidence of collaborative or multidisciplinary interactions for research that are synergistic and/or show the potential to generate transformative science.

We are no longer accepting applications for 2019. Questions or individual requests for funding should be directed to uvabrain@virginia.edu.


Seed Funded Research in the News

Alban Gaultier, Assistant Professor in the Department of Neuroscience led research funded by the UVA Brain Institute which found that depressive symptoms in mice could be reversed by feeding them Lactobacillus, a probiotic found in live-cultures yogurt.

Gautier Research


Seed Funded Research

2019 Awards

A novel, effective microRNA-based gene therapy approach for Rett Syndrome |Sanchita Bhatnagar, PhD – Department of Biochemistry and Molecular Genetics, Howard Goodkin, PhDDepartment of Neurology

Brain Signal Entropy and Oxytocin Receptor Epigenetics: Neurobiological Markers of Social Developmental Variability | Meghan Puglia, PhD – Department of Neurology, Kevin Pelphrey, PhDDepartment of Neurology, James Morris, PhDDepartment of Psychology, Tobias Grossmann, PhD – Department of Psychology, Jessica Connelly, PhD – Department of Psychology

Epigenetic aging is associated with cognitive decline and intrinsic neural connectivity | James Morris, PhD – Department of Psychology, Jessica Connelly, PhDDepartment of Psychology

Epigenetic Consequences of Maternal Oxytocin Treatment in Offspring | Jessica Connelly, PhD – Department of Psychology, Patrick Grant, PhDDepartment of Biochemistry and Molecular Genetics

Facilitating axon regeneration via boosting phagocytosis and an apoptotic metabolite mix | Sarah Kucenas, PhD – Department of Biology, Kodi Ravichandran, PhDDepartment of Microbiology, Immunology and Cancer Biology

Identifying Novel Targets for the Treatment of Opioid Use Disorder  | Wendy Lynch, PhD – Department of Psychiatry and Neurobehavioral Sciences and Neuroscience, Patrick Grant, PhDDepartment of Biochemistry and Molecular Genetics, David Auble, PhDDepartment of Biochemistry and Molecular Genetics

In vivo 2-photon fluorescence lifetime imaging to track metabolic changes in live Alzheimer’s disease model mouse brains | Ammasi Periasamy, PhD – Department of Biology, Andres Norambuena, PhDDepartment of Biology, George Bloom, PhDDepartment of Biology

Investigating the role of the microbiome in early brain and behavioral development | Tobias Grossmann, PhD – Department of Psychology, Jeanne Alhusen, PhDDepartment of Psychology, Caitlin Dreisbach, PhDDepartment of Psychology, Caroline Kelsey, PhD – Department of Psychology

NICU Predictive Analytics for Cognitive and Behavioral Disabilities | Sarah Miller, PhD – Department of Pediatrics, Kevin Pelphrey, PhDDepartment of Neurology, Robert Andris, PhDDepartment of Medicine

The role of microglial P2Y12 receptors in a novel model of temporal lobe epilepsy | Edward Perez-Reyes, PhD – Department of Pharmacology, Ukpong Eyo, PhDDepartment of Neuroscience

Thermal Dose Effects on the Diffusional Properties of Neuronal Tissue | Craig Meyer, PhD – Department of Biomedical Engineering Jeffrey Elias, PhD – Department of Neurosurgery

Transcriptional response of the midbrain dopamine system to stress |Jay Hirsh, PhD – Department of Biology, Jessica Connelly, PhDDepartment of Psychology

HEAL Initiative Seed Grant Program FY 2019

Assessing the Impasse: Identifying Barriers to Collaboration Between Faith-Based and Medication Assisted Treatment Addiction Service Providers | China Scherz, PhD - Assistant Professor of Anthropology

3 Cavalier Awards

The UVA Brain Institute supported funding of ten neuroscience research studies through a new rapid seed funding program developed by the Office of Vice President for Research called 3 Cavaliers.

Automatic Sensing and Characterization of Social Interactions | Laura Barnes, PhD - Department of Systems and Information Engineering, Jennifer Jane Roe, PhD - Center for Design and Health, Bethany Teachman, PhD - Department of Psychology

Building an in vitro Model for Neural Tube Defects | Christine I. Thisse, PhD – Department of Cell Biology, Raymond E. Keller, PhD – Department of Biology, Xiaowei Lu, PhD – Department of Cell Biology

Effects of Perturbation of mRNA Export Pathways on Neuron Function | Marie Louise-Hammarskjold, MD, PhD – Department of Microbiology, George Bloom, PhD – Department of Biology, David Rekosh, PhD – Department of Microbiology

Generation and characterization of a preclinical model to study DDX3X disorder | Sanchita Bhatnagar, PhD – Department of Biochemistry and Molecular Genetics, Michael Wormington, PhD – Department of Biology, Howard Goodkin, MD, PhD – Department of Neurology

Genetic Dissection of Vagal Motor Circuits Controlling Heart Function | John Campbell, PhD – Department of Biology, Hui Zong, PhD – Department of Microbiology, Immunology, and Cancer Biology, Patrice G. Guyenet, PhD – Department of Pharmacology

Genetically-Encoded Norepinephrine Sensors | Jun J Zhu, PhD – Department of Pharmacology, Jill Venton, PhD – Department of Chemistry, Wendy Lynch, PhD – Department of Psychiatry and Neurobehavioral Sciences

Harnessing the Wandering Mind | Zachary Irving, PhD - Department of Philosophy, James Coan, PhD - Department of Psychology, Sonam Kachru, PhD - Department of Religious Studies

Modeling Cerebral Reperfusion Injury using Photoacoustic Microscopy and Oxygen-Sensing Nanoparticles | Yashar Sorena Kalani, MD, PhD – Department of Neurosurgery, Song Hu – Department of Biomedical Engineering , Shayn Peirce-Cottler, PhD – Department of Biomedical Engineering

Neuromuscular Pedicle for Improved Functional Outcome of Novel Muscle Regeneration Scaffolds | Patrick Cottler, PhD – Department of Plastic Surgery, Chris Highley, PhD – Department of Biomedical Engineering, George Joseph Christ, PhD – Department of Biomedical Engineering

Role of Innate Immunity in Impaired Neurodevelopment during Zika Virus Infection | Young Hahn, PhD – Department of Microbiology, Immunology and Cancer Biology, Kevin Janes, PhD – Department of Biomedical Engineering, Chia-Yi Kuan, PhD – Department of Neuroscience

2018 Awards

A novel anti-obesity target: Dopamine signaling in the central circadian pacemaker | Ali Guler, PhD – Department of Biology, Michael Scott, PhD– Department of Pharmacology

A novel model for dyslexia and other language-processing disorders | C. Daniel Meliza, PhD – Department of Psychology, Christopher Deppmann, PhD – Department of Biology, Mark Beenhakker, PhD – Department of Pharmacology

Concussion induced inflammation: A clinical and mechanistic study | Joshua Easter, MD – Department of Emergency Medicine, Donna Broshek, PhD – Department of Psychiatry & Neurobehavioral Sciences, Howard Goodkin, MD, PhD - Department of Neurology, John Lukens, PhD - Department of Neuroscience, Kiel Neumann, PhD – Department of Radiology and Medical Imaging, Matthew Panzer, PhD – Department of Mechanical and Aerospace Engineering, Jacob Resch, PhD – Department of Kinesiology, James Stone, MD, PhD – Department of Radiology and Medical Imaging

Cross-linking antibody tetramers (CATs) to localize and activate immune cell subsets for cancer therapy | Benjamin Purow , MD – Department of Neurology (Neuro-Oncology), Tajie Harris, PhD – Department of Neuroscience

Facilitating axon regeneration by boosting glial-mediated phagocytosis | Sarah Kucenas, PhD – Department of Biology, Kodi Ravichandran, PhD – Department of Microbiology, Immunology, and Cancer Biology

Individual variability in the oxytocinergic system and the development of human sociality | James Morris, PhD – Department of Psychology, Angeline Lillard, PhD– Department of Psychology, Jessica Connelly, PhD– Department of Psychology

Investigation of Recurrent Brain Cancer using Dynamic FDG PET Imaging | Bijoy Kundu, PhD – Department of Radiology and Medical Imaging, David Schiff, MD – Department of Neurology (Neuro-Oncology), Patrice Rehm, MD– Department of Radiology and Medical Imaging, Thomas Muttikkal, MD– Department of Radiology and Medical Imaging

Genetically Encoded Dopamine Sensors | Julius Zhu, PhD – Department of Pharmacology, Wendy Lynch, PhD– Department of Psychiatry & Neurobehavioral Sciences

Optimizing treamtent for Alcohol Use Disorder using Targeted Transcranial Magnetic Stimulation | Nassima Ait-Daoud, MD, David Hamilton, MD, Amit Shane, PhD, Karen Ingersoll, PhD - Psychiatry and Neurobehavioral Sciences

Role of Epigenetics on Early Child Development in Bangladesh | William Petri, MD, PhD – Department of Medicine (Infectious Disease), David Auble, PhD – Department of  Biochemistry & Molecular Genetics

Short non-coding RNAs in autism-related disorders | Anindya Dutta, PhD – Department of  Biochemistry & Molecular Genetics, John Lukens, PhD – Department of Neuroscience

2017 Awards

Understanding the contribution of the oligodendrocyte lineage to depression. | Sarah Kucenas, PhD, - Department of Biology, Christopher Overall, PhD - Department of Neuroscience, Alban Gaultier, PhD - Department of Neuroscience

Remote Suppression of Epileptic Seizures. | Ali Guler, PhD - Department of Biology, Manoj Patel, PhD - Department of Anesthesiology

Automating Glia Neuroimaging. | Daniel Weller, PhD - Department of Electrical an Computer Engineering, Christopher Overall, PhD - Department of Neuroscience, Scott Acton, PhD - Department of Electrical and Computer Engineering, Tajie Harris, PhD - Department of Neuroscience, Gustavo Rohde, PhD - Department of Biomedical Engineering

A Phase I Study Targeting Newly Diagnosed Glioblastoma with anti-CD3 x anti-EGFR Bispecific Antibody Armed T-cells in Combination with Radiation ad Temozolomide. | Camilo Fadul, PhD - Department of Neurology, Lawrence Lum, PhD - Department of Medicine, Hematology and Oncology

SysNimDB: a public resource for characterizing neuro-immunological cell types and disease states in heterogenous trascriptomic datasets. | Christopher Overall, PhD - Department of Neuroscience, Quanguan Gu, PhD - Department of Computer Science, Yanjun Qi, PhD - Department of Computer Science, Abigail Flower, PhD - Department of Systems and Information Engineering

Multiscale Imaging of Cerebrovascular Dysfunction in Traumatic Brain Injury. | Song Hu, PhD - Departmentof Biomedical Engineering, Craig Meyer, PhD - Department of Biomedical Engineering, Wilson Miller, PhD - Department of Radiology and Medical Imaging

Cellular and Molecular Basis of Acoustic Nociception. | Jung-Bum Shin, PhD - Department of Neuroscience, Ali Guler, PhD - Department of Biology