One of the unique features of neurological disorders is that most have no therapy, and none to date have a definitive cure. In most institutions, studies of brain disorders have concentrated on a “reductionist” approach, using independent model systems and isolated brain regions to propose new theories and address specific problems. However, many brain disorders involve several or variable brain areas, and require understanding of multiple regions and pathways to understand their cause and responses to therapy.
UVA has strengths in focused ultrasound research in both technology and application, epilepsy research in fundamental science and leading national trials, and data sciences, and now has the opportunity to capitalize on these recent scientific breakthroughs at UVA, new technologies that we have helped develop and are currently developing, and the proximity of our schools to enable teams of basic, computational and clinical researchers to tackle important neuroscience problems together and to rapidly bring these breakthroughs to the clinic. This work will focus on the following areas: traumatic brain injury, autism, focused ultrasound treatments, and neurodegeneration.